• How it Works: Order, Collect, Ship & Results
  • Collect in seconds with simple, painless mouth swabs
  • Access your DNA insights anytime, anywhere from your secure online portal
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DNA Cardiovascular Risk Test (ApoE)

DNA Cardiovascular Risk Test (ApoE)

£180.00 GBP
£180.00 GBP
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Ever wonder why cholesterol-lowering diets have a significant effect on some people but not on others? A large part of the answer lies in your DNA. The Genofit DNA Cardiovascular Risk Test analyzes your APOE gene, a primary genetic factor influencing how your body metabolizes fats and cholesterol.

With a simple and painless cheek swab, this test helps you:

  • Discover your APOE genotype (e.g., e3/e3, e4/e4 etc.).
  • Understand how your body processes fats and cholesterol.
  • Learn your genetic risk for high LDL ("bad") cholesterol.
Turnaround Time
4-6 weeks
Sample Type
Mouth Swabs
Genes Tested
APOE
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Benefits You’ll Love

Easy, Painless Mouth Swabs

Free delivery on all orders

Private & Confidential

Actionable Genetic Insights

Get Started in 3 Easy Steps

  • 1. Purchase Kit

    Order a Genofit test online and we'll ship your test kit directly to your doorstep.

  • 2. Collect & Mail

    Simply collect your sample at home, then mail your sample directly to the laboratory.

  • 3. Receive Results

    Download your report from your secure online account shortly after the lab receives your sample.

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The APOE Gene & Your Heart Health

While family history is a known risk factor for heart disease, it's not just about habits. Your APOE gene is a key genetic factor that directs how your body manages cholesterol and fats, acting as a "cholesterol traffic controller" in your bloodstream.

The specific combination of APOE variants you inherit from your parents determines how this system functions, which in turn affects your risk for conditions like high cholesterol and atherosclerosis. Understanding your APOE genotype provides clear insight into how your body is uniquely wired to handle cholesterol.

Understanding Your APOE Gene Analysis

The DNA Cardiovascular Risk Test analyzes the APOE gene to determine which combination of the three major variants you've inherited. Everyone carries two copies of the APOE gene (one from each parent), creating six possible genetic combinations that influence cardiovascular risk and treatment response.

  • APOE e2 (The Protective Variant): This variant is linked to lower LDL ("bad") cholesterol and a reduced genetic risk for cardiovascular issues.
  • APOE e3 (The Neutral Variant): The most common variant, representing an average genetic risk. For this group, lifestyle choices are the primary factor in cardiovascular health.
  • APOE e4 (The Higher-Risk Variant): Linked to an increased risk for high cholesterol and heart disease, suggesting that preventative health measures may be particularly effective.

Your Genetic Combinations

Since you inherit one APOE variant from each parent, six combinations are possible:

  • e2/e2 (Lowest Genetic Risk): Found in 1-2% of the population. Associated with the most favorable genetic profile for cholesterol management.
  • e2/e3 (Lower Genetic Risk): Found in 10-15% of the population. A protective combination linked to efficient cholesterol handling.
  • e2/e4 (Mixed Genetic Profile): Found in 2-5% of the population. This profile has both protective (e2) and risk-increasing (e4) factors that require a personalized health assessment.
  • e3/e3 (Standard Genetic Risk): The most common profile, found in 50-60% of the population. Risk is primarily determined by lifestyle factors.
  • e3/e4 (Moderately Increased Risk): Found in 20-25% of the population. A proactive approach to heart health is often beneficial for this group.
  • e4/e4 (Highest Genetic Risk): Found in 1-3% of the population. This profile indicates the highest genetic predisposition, making preventative strategies very important.

Why Genofit?

  • Trusted for Accuracy

    Our laboratory meets the highest standards with globally recognized accreditations to deliver reliable results every time.

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  • Your Privacy Matters

    We prioritize your privacy with a password-protected online portal, ensuring that your results are accessible only to you.

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  • Support From Experts

    Our dedicated customer care team is ready to guide you through every step, answer your questions, and provide the assistance you need.

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