The Science Behind Alcohol Intolerance

The Science Behind Alcohol Intolerance

Do you experience flushing, nausea, or headaches after just a small amount of alcohol? You might be one of many people who struggle with alcohol intolerance, a condition where your body has difficulty breaking down alcohol. The good news is that understanding your genetics can shed light on why this happens and how to manage it better. Genofit's DNA Alcohol Intolerance Test offers a simple, at-home solution to uncover how your genes influence your reaction to alcohol.

What Is Alcohol Intolerance?

Alcohol intolerance occurs when your body cannot efficiently process alcohol, primarily due to genetic variations in how enzymes handle this substance. Normally, your liver breaks down alcohol in two steps:

  1. Alcohol is converted to acetaldehyde by enzymes called alcohol dehydrogenase (ADH).
  2. Acetaldehyde is broken down into a harmless substance called acetate by aldehyde dehydrogenase (ALDH).

However, genetic variations can disrupt these steps. For instance:

  • ADH1B and ADH1C genes may cause alcohol to convert to acetaldehyde too quickly, overwhelming your system.
  • ALDH2 variations can slow the process of converting acetaldehyde to acetate, leading to a toxic buildup in your body.

This imbalance causes symptoms like facial flushing, nausea, and an increased risk for health conditions like esophageal cancer. Alcohol intolerance is more common in certain ethnic groups and often runs in families.

How Can the DNA Alcohol Intolerance Test Help?

The Genofit DNA Alcohol Intolerance Test is designed to help you uncover your body's unique genetic blueprint for alcohol metabolism. By analyzing key genetic variants in the ADH1B, ADH1C, and ALDH2 genes, this test reveals how your body processes alcohol and why you may experience discomfort or health risks.

Key Benefits of the Test:

  • Personalized Insights: Understand your genetic predisposition to alcohol intolerance and the potential for health concerns.
  • Painless Sampling: Collect your DNA using a simple mouth swab – no needles or blood required.
  • Convenient and Confidential: Mail your sample from home and receive your results securely online in 6-8 weeks.

How It Works

  1. Collect DNA Samples: The kit includes easy-to-use mouth swabs for quick, painless sample collection.
  2. Mail Samples to the Lab: Use the provided envelope to send your samples for analysis.
  3. Receive Results: Access your detailed results in your secure online portal, complete with insights into your alcohol metabolism.

The Genetics Behind Alcohol Metabolism

Your body's response to alcohol is deeply rooted in genetics. The DNA Alcohol Intolerance Test focuses on three critical gene variants:

Gene Variant Impact
ADH1B rs1229984 Converts alcohol to acetaldehyde faster, causing quicker and more intense symptoms.
ADH1C rs1693482 Increases acetaldehyde production, contributing to intolerance symptoms.
ALDH2 rs671 Slows down acetaldehyde clearance, leading to stronger reactions and higher health risks.

By analyzing these variants, the test helps you understand why you react to alcohol the way you do and empowers you to make informed decisions about your drinking habits.

Why Take the Test?

Beyond discomfort, alcohol intolerance can have serious health implications. Prolonged exposure to acetaldehyde, due to genetic variations, is linked to a heightened risk of esophageal cancer and other health issues. By identifying your genetic risks, you can take proactive steps to protect your health, such as moderating alcohol intake or avoiding it altogether.

The Genofit DNA Alcohol Intolerance Test is a valuable tool for anyone curious about their body's unique relationship with alcohol. Whether you're looking to understand your symptoms or make healthier lifestyle choices, this test offers clear answers.


Take control of your health and drinking habits today. Order the Genofit DNA Alcohol Intolerance Test for $149 and discover how your genes affect your reaction to alcohol. With just a simple mouth swab, you can gain insights to make informed, confident decisions about your well-being.

Order Now and get started on your journey to understanding alcohol intolerance!

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