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Osteoporosis and Osteoarthritis
Osteoporosis is a disease characterized by weak and brittle bones. People with osteoporosis are highly susceptible to bone fractures, often with minimal trauma. It’s a disease affecting the elderly that becomes more apparent with age. Fractures from osteoporosis are more common than heart attack, stroke and breast cancer combined.
Osteoarthritis is a joint disease characterized by the breakdown of the protective cartilage within joints and surrounding bone tissue. People with osteoarthritis suffer from joint swelling, pain and reduced joint motion. Commonly affected joints are in the hands, lower back, hips and knees.
Take this test to see whether you have inherited any genetic variants that compromise the health of your bones and joints.
The Genetics
By understanding your genetic susceptibility to osteoporosis, you can implement strategies early to delay the onset of bone health complications and reduce the severity of bone loss.
Variants Tested:
- CYP2R1 – Increases the risk of vitamin D deficiency, leading to reduced absorption of calcium. Adequate calcium is essential for healthy bones.
- GC – Increases the risk of vitamin D deficiency and reduced absorption of calcium.
- WNT16 – Increases the risk of reduced bone formation.
- GDF5 – Affects the normal regulation of the maintenance, development and repair of bones, joints and cartilage.
- COL1A1 – Affects the formation of collagen (an essential strength and structural component of bones).
Strong, healthy bones are important for providing structure, anchoring muscles and ligaments, protecting our internal organs and storing essential minerals.
From birth until the age of 30, new bone is produced more quickly than old bone is broken down, reaching a peak bone mass at approximately 30 years of age. Bone remodelling continues throughout adulthood, but bone mass slowly decreases, as the old bone removal is quicker than new bone production. Poor bone growth as a child, and greater than normal bone loss as an adult can both contribute towards an increased risk of osteoporosis.
CLIA Certified
All Genofit tests are guaranteed to be processed by a CLIA certified laboratory–the same type of certification as hospital laboratories.
Physician Reviewed
Genofit tests are reviewed and approved by a third-party independent physician licensed to practice within your state.
HIPAA Compliant
Genofit takes measures to guarantee your privacy. Your personal data is securely stored and will not shared with any third-party without your permission.
Get Started in 3 Easy Steps​
1. Activate Kit
2. Collect & Mail
3. View Results
Get Started in 3 Easy Steps
1. Activate Kit
Activate your kit online at genofit.com by entering the unique activation code found inside your kit.
2. Collect & Mail Sample
Simply collect your sample at home, then mail your sample directly to the lab with free return shipping.
3. View Results
Receive your results within 5-7 business days after the lab receives your kit.
FAQ's
Here are the answers to the most frequently asked questions about this test.
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